保护基因组学或能改善湖鲟鱼的未来

GLFT-funded Researchers Advance Use of SNP Data

Lake sturgeon (Acipenser fulvescens) are an ecologically and culturally significant species throughout the Great Lakes. Yet, populations have been estimated at one percent of historic levels due to multiple human-caused reasons such as overfishing, habitat loss or degradation, and barriers to suitable habitat from dams. Consequently, lake sturgeon is listed as either endangered or threatened in 19 U.S. states and as threatened in Canada. Conservation genomics is proving to be a valuable tool for researchers and fishery managers keen to properly manage and regulate the lake sturgeon fishery in the Great Lakes. This edition of 研究笔记 highlights research contributions on lake sturgeon supported by the Great Lakes Fishery Trust.

From 2015 to 2019, a research team led by Dr. Amy Welsh with West Virginia University studied the adaptive genetic diversity of 16 lake sturgeon spawning populations. Dr. Welsh, joined by Eric Normandeau and Louis Bernatchez, both with Université Laval, analyzed the genetic variations of these populations using single nucleotide polymorphisms (SNPs) that included neutral and adaptive variation. Then, the team grouped populations based on similarities in adaptive traits to identify potential management units meant to help conserve the lake sturgeon’s adaptive potential.

主要发现

• The research team found the SNP data provided much greater resolution and increased power of assignment testing than microsatellites used in some genetic research.
• The team proposed seven refined management units in the Great Lakes that use spawning location SNP data and geography to inform population selection for stocking by fishery managers.

湖鲟研究取得重大成果

The GLFT-supported research is advancing scientific knowledge of lake sturgeon ecology and the role of genomics in conservation. Previous analyses of the lake sturgeon population structure were based on neutral genetic data, which track roles of migration and genetic drift to determine population structure. Dr. Welsh’s team improved the understanding of how adaptive variation is distributed. Furthermore, the refined management units proposed by the team, if enacted, may result in the conservation of the adaptive potential of lake sturgeon populations, a primary goal of conservation genetics.

Research Spinoff

A collaboration between the research team and another GLFT-supported researcher, Dr. Wesley Larson, previously of University of Wisconsin–Stevens Point and now with the National Oceanic and Atmospheric Administration, developed a panel consisting of 258 SNPs for future assignment testing and parentage analysis using data generated from this project. The Great Lakes Fish and Wildlife Restoration Act funded the spinoff project.